Health Benefits Effective Venom Immunotherapy Reported to cause Guillain-Barré syndrome and chronic inflammation of hair follicles.Risk of adverse reactions (including anaphylaxis) in people allergic to bee venom.Insufficient evidence for most benefits.Preliminary evidence found it can reduce Th2 cytokines while increasing Tregs, thus preventing allergic symptoms. However, it also has some potential immunoprotective effects. The enzyme phospholipase A 2 triggers inflammation by causing a massive release of arachidonic acid from cell membranes. Its other less abundant peptides (apamin and adolapin) act as defensive toxins but preliminary evidence suggests they may also have anti-inflammatory and pain-relieving activity through similar mechanisms. They block several pro-inflammatory pathways, resulting in a reduced production of cytokines (such as IL1-beta, IL-6, and TNF-alpha) and messengers ( prostaglandins and nitric oxide). Īlthough melittin causes itching, pain, and inflammation when delivered at high doses (such as when being stung by a bee), smaller amounts have anti-inflammatory properties. This substance is responsible for many of its potential therapeutic effects since it had antibacterial, antiviral, and anticancer activities in cell-based studies. Of these, the peptide melittin makes up approximately 50% of bee venom. Peptides (such as melittin, apamin, and adolapin).The venom contains many active components, including : Components of Bee Venomīee venom, also known as apitoxin, is a bitter, colorless liquid mainly composed of proteins that causes inflammation and is used by bees for defensive purposes. Īlthough the evidence to support these uses is generally insufficient due to the lack of well-controlled clinical trials, proponents claim it can be used for many conditions, including :īee venom is also routinely used in venom immunotherapy, which consists of exposing allergic people to gradually higher doses of the venom with the intention of altering the immune response and reducing allergic symptoms in case of a bee sting. In both cases, the venom can be administered systemically or in the form of chemical stimulation of acupoints, so-called “bee venom acupuncture” or “apipuncture”. Alternatively, the term ‘bee venom therapy’ is more commonly employed when the venom is injected with a syringe. īee sting therapy consists of directly injecting the sting from a live bee placed on the skin and intentionally leaving the venom sac in the tissue for therapeutic purposes. More recently, this therapy has experienced a surge in popularity among alternative practitioners worldwide. Live bee sting therapy, also known as Bong-Chim or bee venom therapy, is a traditional therapy with bee venom originated in Greece and China and popularly used in several Asian countries, especially Korea, for a variety of conditions. But are its purported benefits backed by science? And what are its main risks? Read below to find out. Proponents claim that it helps with chronic pain, inflammatory conditions, Parkinson’s, and even cancer. A plus sign next to the number “” means that the information is found within the full scientific study rather than the abstract.īee sting therapy is a treatment traditionally used in Asian countries that is gaining popularity among alternative practitioners worldwide. Note that each number in parentheses is a clickable link to peer-reviewed scientific studies. ![]() If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at. Our goal is to not have a single piece of inaccurate information on this website. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. ![]() Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists.Īll of our content is written by scientists and people with a strong science background. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. ![]() We believe that the most accurate information is found directly in the scientific source. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed.
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